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Intestinal damage precedes mucosal immune dysfunction in SIV infection
HIV and pathogenic SIV infection are characterized by mucosal dysfunction including epithelial barrier damage, loss of Th17 cells, neutrophil infiltration, and microbial translocation with accompanying inflammation. However, it is unclear how and when these contributing factors occur relative to one...
Autores principales: | Hensley-McBain, Tiffany, Berard, Alicia R., Manuzak, Jennifer A., Miller, Charlene J., Zevin, Alexander S., Polacino, Patricia, Gile, Jillian, Agricola, Brian, Cameron, Mark, Hu, Shiu-Lok, Estes, Jacob D., Reeves, R. Keith, Smedley, Jeremy, Keele, Brandon F., Burgener, Adam D., Klatt, Nichole R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162106/ https://www.ncbi.nlm.nih.gov/pubmed/29907866 http://dx.doi.org/10.1038/s41385-018-0032-5 |
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