The JAK inhibitor ruxolitinib reduces inflammation in an ILC3-independent model of innate immune colitis

Innate immunity contributes to the pathogenesis of inflammatory bowel disease (IBD). However, the mechanisms of IBD mediated by innate immunity are incompletely understood and there are limited models of spontaneous innate immune colitis to address this question. Here we describe a new robust model...

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Detalles Bibliográficos
Autores principales: Overstreet, A.M., LaTorre, D.L., Abernathy-Close, L., Murphy, S.F., Rhee, L., Boger, A.M., Adlaka, K.R., Iverson, A.M., Bakke, D.S., Weber, C.R., Boone, D.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162142/
https://www.ncbi.nlm.nih.gov/pubmed/29988117
http://dx.doi.org/10.1038/s41385-018-0051-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162142/
https://www.ncbi.nlm.nih.gov/pubmed/29988117
http://dx.doi.org/10.1038/s41385-018-0051-2

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