Identification and pharmaceutical evaluation of novel frog skin-derived serine proteinase inhibitor peptide–PE-BBI (Pelophylax esculentus Bowman-Birk inhibitor) for the potential treatment of cancer

Amphibian venom-derived peptides have high potential in the field of anticancer drug discovery. We have isolated a novel Bowman-Birk proteinase inhibitor (BBI)-type peptide from the skin secretion of Pelophylax esculentus (PE) named PE-BBI, and evaluated its bio-functions and anti-cancer activity in...

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Detalles Bibliográficos
Autores principales: Lyu, Peng, Ge, Lilin, Ma, Rui, Wei, Ran, McCrudden, Cian M., Chen, Tianbao, Shaw, Chris, Kwok, Hang Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162207/
https://www.ncbi.nlm.nih.gov/pubmed/30267012
http://dx.doi.org/10.1038/s41598-018-32947-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162207/
https://www.ncbi.nlm.nih.gov/pubmed/30267012
http://dx.doi.org/10.1038/s41598-018-32947-5

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