Shikonin Inhibits Tumor Growth in Mice by Suppressing Pyruvate Kinase M2-mediated Aerobic Glycolysis

Shift metabolism profile from mitochondrial oxidative phosphorylation to aerobic glycolysis (Warburg effect) is a key for tumor cell growth and metastasis. Therefore, suppressing the tumor aerobic glycolysis shows a great promise in anti-tumor therapy. In the present study, we study the role of shik...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaoyue, Zhu, Yanan, Hu, Jianhua, Jiang, Longwei, Li, Limin, Jia, Shaochang, Zen, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162216/
https://www.ncbi.nlm.nih.gov/pubmed/30266938
http://dx.doi.org/10.1038/s41598-018-31615-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162216/
https://www.ncbi.nlm.nih.gov/pubmed/30266938
http://dx.doi.org/10.1038/s41598-018-31615-y

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