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Three-Dimensional Retinal Organoids Facilitate the Investigation of Retinal Ganglion Cell Development, Organization and Neurite Outgrowth from Human Pluripotent Stem Cells

Retinal organoids are three-dimensional structures derived from human pluripotent stem cells (hPSCs) which recapitulate the spatial and temporal differentiation of the retina, serving as effective in vitro models of retinal development. However, a lack of emphasis has been placed upon the developmen...

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Detalles Bibliográficos
Autores principales: Fligor, Clarisse M., Langer, Kirstin B., Sridhar, Akshayalakshmi, Ren, Yuan, Shields, Priya K., Edler, Michael C., Ohlemacher, Sarah K., Sluch, Valentin M., Zack, Donald J., Zhang, Chi, Suter, Daniel M., Meyer, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162218/
https://www.ncbi.nlm.nih.gov/pubmed/30266927
http://dx.doi.org/10.1038/s41598-018-32871-8