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Three-Dimensional Retinal Organoids Facilitate the Investigation of Retinal Ganglion Cell Development, Organization and Neurite Outgrowth from Human Pluripotent Stem Cells
Retinal organoids are three-dimensional structures derived from human pluripotent stem cells (hPSCs) which recapitulate the spatial and temporal differentiation of the retina, serving as effective in vitro models of retinal development. However, a lack of emphasis has been placed upon the developmen...
Autores principales: | Fligor, Clarisse M., Langer, Kirstin B., Sridhar, Akshayalakshmi, Ren, Yuan, Shields, Priya K., Edler, Michael C., Ohlemacher, Sarah K., Sluch, Valentin M., Zack, Donald J., Zhang, Chi, Suter, Daniel M., Meyer, Jason S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162218/ https://www.ncbi.nlm.nih.gov/pubmed/30266927 http://dx.doi.org/10.1038/s41598-018-32871-8 |
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