Intracellular nucleosomes constrain a DNA linking number difference of −1.26 that reconciles the Lk paradox

The interplay between chromatin structure and DNA topology is a fundamental, yet elusive, regulator of genome activities. A paradigmatic case is the “linking number paradox” of nucleosomal DNA, which refers to the incongruence between the near two left-handed superhelical turns of DNA around the his...

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Detalles Bibliográficos
Autores principales: Segura, Joana, Joshi, Ricky S., Díaz-Ingelmo, Ofelia, Valdés, Antonio, Dyson, Silvia, Martínez-García, Belén, Roca, Joaquim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162219/
https://www.ncbi.nlm.nih.gov/pubmed/30266901
http://dx.doi.org/10.1038/s41467-018-06547-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162219/
https://www.ncbi.nlm.nih.gov/pubmed/30266901
http://dx.doi.org/10.1038/s41467-018-06547-w

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