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Intracellular nucleosomes constrain a DNA linking number difference of −1.26 that reconciles the Lk paradox
The interplay between chromatin structure and DNA topology is a fundamental, yet elusive, regulator of genome activities. A paradigmatic case is the “linking number paradox” of nucleosomal DNA, which refers to the incongruence between the near two left-handed superhelical turns of DNA around the his...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162219/ https://www.ncbi.nlm.nih.gov/pubmed/30266901 http://dx.doi.org/10.1038/s41467-018-06547-w |