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MiR-532-5p suppresses renal cancer cell proliferation by disrupting the ETS1-mediated positive feedback loop with the KRAS-NAP1L1/P-ERK axis

BACKGROUND: Despite the fact that miRNAs play pivotal roles in various human malignancies, their molecular mechanisms influencing RCC are poorly understood. METHODS: The expression of miRNAs from RCC and paired normal renal specimens was analysed by a combined computational and experimental approach...

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Detalles Bibliográficos
Autores principales: Zhai, Wei, Ma, Junjie, Zhu, Rujian, Xu, Chen, Zhang, Jin, Chen, Yonghui, Chen, Zhiguo, Gong, Dongkui, Zheng, Jiayi, Chen, Chen, Li, Saiyang, Li, Butang, Huang, Yiran, Xue, Wei, Zheng, Junhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162242/
https://www.ncbi.nlm.nih.gov/pubmed/30082686
http://dx.doi.org/10.1038/s41416-018-0196-5