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MiR-532-5p suppresses renal cancer cell proliferation by disrupting the ETS1-mediated positive feedback loop with the KRAS-NAP1L1/P-ERK axis
BACKGROUND: Despite the fact that miRNAs play pivotal roles in various human malignancies, their molecular mechanisms influencing RCC are poorly understood. METHODS: The expression of miRNAs from RCC and paired normal renal specimens was analysed by a combined computational and experimental approach...
Autores principales: | Zhai, Wei, Ma, Junjie, Zhu, Rujian, Xu, Chen, Zhang, Jin, Chen, Yonghui, Chen, Zhiguo, Gong, Dongkui, Zheng, Jiayi, Chen, Chen, Li, Saiyang, Li, Butang, Huang, Yiran, Xue, Wei, Zheng, Junhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162242/ https://www.ncbi.nlm.nih.gov/pubmed/30082686 http://dx.doi.org/10.1038/s41416-018-0196-5 |
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