Systems biology approach reveals a link between mTORC1 and G2/M DNA damage checkpoint recovery

Checkpoint recovery, the process that checkpoint-arrested cells with normal DNA repair capacity resume cell cycle progression, is essential for genome stability. However, the signaling network of the process has not been clearly defined. Here, we combine functional proteomics, mathematical modeling,...

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Detalles Bibliográficos
Autores principales: Hsieh, Hui-Ju, Zhang, Wei, Lin, Shu-Hong, Yang, Wen-Hao, Wang, Jun-Zhong, Shen, Jianfeng, Zhang, Yiran, Lu, Yiling, Wang, Hua, Yu, Jane, Mills, Gordon B., Peng, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162282/
https://www.ncbi.nlm.nih.gov/pubmed/30266942
http://dx.doi.org/10.1038/s41467-018-05639-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162282/
https://www.ncbi.nlm.nih.gov/pubmed/30266942
http://dx.doi.org/10.1038/s41467-018-05639-x

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