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IFITM proteins inhibit HIV-1 protein synthesis

Interferon induced transmembrane proteins (IFITMs) inhibit the cellular entry of a broad range of viruses, but it has been suspected that for HIV-1 IFITMs may also inhibit a post-integration replicative step. We show that IFITM expression reduces HIV-1 viral protein synthesis by preferentially exclu...

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Detalles Bibliográficos
Autores principales: Lee, Wing-Yiu Jason, Fu, Rebecca Menhua, Liang, Chen, Sloan, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162285/
https://www.ncbi.nlm.nih.gov/pubmed/30266929
http://dx.doi.org/10.1038/s41598-018-32785-5