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The lipid mediator lysophosphatidic acid induces folding of disordered peptides with basic amphipathic character into rare conformations
Membrane-active, basic amphipathic peptides represent a class of biomolecules with diverse functions. Sequentially close protein segments also show similar behaviour in several ways. Here we investigated the effect of the lipid mediator lysophosphatidic acid (LPA) on the conformation of structurally...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162328/ https://www.ncbi.nlm.nih.gov/pubmed/30266943 http://dx.doi.org/10.1038/s41598-018-32786-4 |