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Antibodies Set Boundaries Limiting Microbial Metabolite Penetration and the Resultant Mammalian Host Response

Although the mammalian microbiota is well contained within the intestine, it profoundly shapes development and metabolism of almost every host organ. We questioned the range and depth of microbial metabolite penetration into the host, and how this is modulated by intestinal immunity. Chemically iden...

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Detalles Bibliográficos
Autores principales: Uchimura, Yasuhiro, Fuhrer, Tobias, Li, Hai, Lawson, Melissa A., Zimmermann, Michael, Yilmaz, Bahtiyar, Zindel, Joel, Ronchi, Francesca, Sorribas, Marcel, Hapfelmeier, Siegfried, Ganal-Vonarburg, Stephanie C., Gomez de Agüero, Mercedes, McCoy, Kathy D., Sauer, Uwe, Macpherson, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162337/
https://www.ncbi.nlm.nih.gov/pubmed/30193848
http://dx.doi.org/10.1016/j.immuni.2018.08.004