Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80

The approximately thirty core subunits of kinetochores assemble on centromeric chromatin containing the histone H3 variant CENP-A and connect chromosomes with spindle microtubules. The chromatin proximal 16-subunit CCAN (constitutive centromere associated network) creates a mechanically stable bridg...

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Detalles Bibliográficos
Autores principales: Pesenti, Marion E., Prumbaum, Daniel, Auckland, Philip, Smith, Charlotte M., Faesen, Alex C., Petrovic, Arsen, Erent, Muriel, Maffini, Stefano, Pentakota, Satyakrishna, Weir, John R., Lin, Yu-Chih, Raunser, Stefan, McAinsh, Andrew D., Musacchio, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162344/
https://www.ncbi.nlm.nih.gov/pubmed/30174292
http://dx.doi.org/10.1016/j.molcel.2018.07.038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162344/
https://www.ncbi.nlm.nih.gov/pubmed/30174292
http://dx.doi.org/10.1016/j.molcel.2018.07.038

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