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Targeting Raf Kinase Inhibitory Protein Regulation and Function

Raf Kinase Inhibitory Protein (RKIP) is a highly conserved kinase inhibitor that functions as a metastasis suppressor in a variety of cancers. Since RKIP can reprogram tumor cells to a non-metastatic state by rewiring kinase networks, elucidating the mechanism by which RKIP acts not only reveals mol...

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Detalles Bibliográficos
Autores principales: Yesilkanal, Ali Ekrem, Rosner, Marsha Rich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162369/
https://www.ncbi.nlm.nih.gov/pubmed/30181452
http://dx.doi.org/10.3390/cancers10090306