Targeting Focal Adhesion Kinase Using Inhibitors of Protein-Protein Interactions

Focal adhesion kinase (FAK) is a cytoplasmic non-receptor protein tyrosine kinase that is overexpressed and activated in many human cancers. FAK transmits signals to a wide range of targets through both kinase-dependant and independent mechanism thereby playing essential roles in cell survival, prol...

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Detalles Bibliográficos
Autores principales: Mousson, Antoine, Sick, Emilie, Carl, Philippe, Dujardin, Denis, De Mey, Jan, Rondé, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162372/
https://www.ncbi.nlm.nih.gov/pubmed/30134553
http://dx.doi.org/10.3390/cancers10090278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162372/
https://www.ncbi.nlm.nih.gov/pubmed/30134553
http://dx.doi.org/10.3390/cancers10090278

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