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Targeting Focal Adhesion Kinase Using Inhibitors of Protein-Protein Interactions

Focal adhesion kinase (FAK) is a cytoplasmic non-receptor protein tyrosine kinase that is overexpressed and activated in many human cancers. FAK transmits signals to a wide range of targets through both kinase-dependant and independent mechanism thereby playing essential roles in cell survival, prol...

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Detalles Bibliográficos
Autores principales:	Mousson, Antoine, Sick, Emilie, Carl, Philippe, Dujardin, Denis, De Mey, Jan, Rondé, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162372/ https://www.ncbi.nlm.nih.gov/pubmed/30134553 http://dx.doi.org/10.3390/cancers10090278

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