CAR-T Cells Based on Novel BCMA Monoclonal Antibody Block Multiple Myeloma Cell Growth

The cell-surface protein B cell maturation antigen (BCMA, CD269) has emerged as a promising target for CAR-T cell therapy for multiple myeloma. In order to create a novel BCMA CAR, we generated a new BCMA monoclonal antibody, clone 4C8A. This antibody exhibited strong and selective binding to human...

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Detalles Bibliográficos
Autores principales: Berahovich, Robert, Zhou, Hua, Xu, Shirley, Wei, Yuehua, Guan, Jasper, Guan, Jian, Harto, Hizkia, Fu, Shuxiang, Yang, Kaihuai, Zhu, Shuying, Li, Le, Wu, Lijun, Golubovskaya, Vita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162381/
https://www.ncbi.nlm.nih.gov/pubmed/30208593
http://dx.doi.org/10.3390/cancers10090323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162381/
https://www.ncbi.nlm.nih.gov/pubmed/30208593
http://dx.doi.org/10.3390/cancers10090323

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