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CAR-T Cells Based on Novel BCMA Monoclonal Antibody Block Multiple Myeloma Cell Growth

The cell-surface protein B cell maturation antigen (BCMA, CD269) has emerged as a promising target for CAR-T cell therapy for multiple myeloma. In order to create a novel BCMA CAR, we generated a new BCMA monoclonal antibody, clone 4C8A. This antibody exhibited strong and selective binding to human...

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Detalles Bibliográficos
Autores principales:	Berahovich, Robert, Zhou, Hua, Xu, Shirley, Wei, Yuehua, Guan, Jasper, Guan, Jian, Harto, Hizkia, Fu, Shuxiang, Yang, Kaihuai, Zhu, Shuying, Li, Le, Wu, Lijun, Golubovskaya, Vita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162381/ https://www.ncbi.nlm.nih.gov/pubmed/30208593 http://dx.doi.org/10.3390/cancers10090323

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