A Statistical Method for Observing Personal Diploid Methylomes and Transcriptomes with Single-Molecule Real-Time Sequencing

We address the problem of observing personal diploid methylomes, CpG methylome pairs of homologous chromosomes that are distinguishable with respect to phased heterozygous variants (PHVs), which is challenging due to scarcity of PHVs in personal genomes. Single molecule real-time (SMRT) sequencing i...

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Detalles Bibliográficos
Autores principales: Suzuki, Yuta, Wang, Yunhao, Au, Kin Fai, Morishita, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162384/
https://www.ncbi.nlm.nih.gov/pubmed/30235838
http://dx.doi.org/10.3390/genes9090460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162384/
https://www.ncbi.nlm.nih.gov/pubmed/30235838
http://dx.doi.org/10.3390/genes9090460

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