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Preclinical Evaluation of [(68)Ga]Ga-DFO-ZEGFR:2377: A Promising Affibody-Based Probe for Noninvasive PET Imaging of EGFR Expression in Tumors

Radionuclide imaging of epidermal growth factor receptor (EGFR) expression in tumors may stratify patients for EGFR-targeting therapies and predict response or resistance to certain treatments. Affibody molecules, which are nonimmunoglobulin scaffold proteins, have a high potential as probes for mol...

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Detalles Bibliográficos
Autores principales: Oroujeni, Maryam, Garousi, Javad, Andersson, Ken G., Löfblom, John, Mitran, Bogdan, Orlova, Anna, Tolmachev, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162391/
https://www.ncbi.nlm.nih.gov/pubmed/30231504
http://dx.doi.org/10.3390/cells7090141