HDAC Inhibition Counteracts Metastatic Re-Activation of Prostate Cancer Cells Induced by Chronic mTOR Suppression

This study was designed to investigate whether epigenetic modulation by histone deacetylase (HDAC) inhibition might circumvent resistance towards the mechanistic target of rapamycin (mTOR) inhibitor temsirolimus in a prostate cancer cell model. Parental (par) and temsirolimus-resistant (res) PC3 pro...

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Detalles Bibliográficos
Autores principales: Makarević, Jasmina, Rutz, Jochen, Juengel, Eva, Maxeiner, Sebastian, Mani, Jens, Vallo, Stefan, Tsaur, Igor, Roos, Frederik, Chun, Felix K.-H., Blaheta, Roman A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162415/
https://www.ncbi.nlm.nih.gov/pubmed/30200497
http://dx.doi.org/10.3390/cells7090129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162415/
https://www.ncbi.nlm.nih.gov/pubmed/30200497
http://dx.doi.org/10.3390/cells7090129

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