Role of Presenilin in Mitochondrial Oxidative Stress and Neurodegeneration in Caenorhabditis elegans

Neurodegenerative diseases like Alzheimer’s disease (AD) are poised to become a global health crisis, and therefore understanding the mechanisms underlying the pathogenesis is critical for the development of therapeutic strategies. Mutations in genes encoding presenilin (PSEN) occur in most familial...

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Detalles Bibliográficos
Autores principales: Sarasija, Shaarika, Norman, Kenneth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162450/
https://www.ncbi.nlm.nih.gov/pubmed/30149498
http://dx.doi.org/10.3390/antiox7090111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162450/
https://www.ncbi.nlm.nih.gov/pubmed/30149498
http://dx.doi.org/10.3390/antiox7090111

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