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Platelet-Rich Plasma Prevents In Vitro Transforming Growth Factor-β1-Induced Fibroblast to Myofibroblast Transition: Involvement of Vascular Endothelial Growth Factor (VEGF)-A/VEGF Receptor-1-Mediated Signaling †

The antifibrotic potential of platelet-rich plasma (PRP) is controversial. This study examined the effects of PRP on in vitro transforming growth factor (TGF)-β1-induced differentiation of fibroblasts into myofibroblasts, the main drivers of fibrosis, and the involvement of vascular endothelial grow...

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Detalles Bibliográficos
Autores principales: Chellini, Flaminia, Tani, Alessia, Vallone, Larissa, Nosi, Daniele, Pavan, Paola, Bambi, Franco, Zecchi Orlandini, Sandra, Sassoli, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162453/
https://www.ncbi.nlm.nih.gov/pubmed/30235859
http://dx.doi.org/10.3390/cells7090142