Melatonin Sensitizes Hepatocellular Carcinoma Cells to Chemotherapy Through Long Non-Coding RNA RAD51-AS1-Mediated Suppression of DNA Repair

DNA repair systems are abnormally active in most hepatocellular carcinoma (HCC) cells due to accumulated mutations, resulting in elevated DNA repair capacity and resistance to chemotherapy and radiotherapy. Thus, targeting DNA repair mechanisms is a common treatment approach in HCC to sensitize canc...

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Detalles Bibliográficos
Autores principales: Chen, Chin-Chuan, Chen, Chi-Yuan, Wang, Shu-Huei, Yeh, Chau-Ting, Su, Shih-Chi, Ueng, Shir-Hwa, Chuang, Wen-Yu, Hsueh, Chuen, Wang, Tong-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162454/
https://www.ncbi.nlm.nih.gov/pubmed/30201872
http://dx.doi.org/10.3390/cancers10090320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162454/
https://www.ncbi.nlm.nih.gov/pubmed/30201872
http://dx.doi.org/10.3390/cancers10090320

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