Repeated Intrastriatal Botulinum Neurotoxin-A Injection in Hemiparkinsonian Rats Increased the Beneficial Effect on Rotational Behavior

Injection of botulinum neurotoxin-A (BoNT-A) into the striatum of hemiparkinsonian (hemi-PD) rats reduced apomorphine-induced rotation behavior significantly, for at least 3 months. Thereafter, rotation behavior increased again. We injected hemi-PD rats with 1 ng BoNT-A twice, the second injection f...

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Detalles Bibliográficos
Autores principales: Hawlitschka, Alexander, Holzmann, Carsten, Wree, Andreas, Antipova, Veronica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162461/
https://www.ncbi.nlm.nih.gov/pubmed/30208596
http://dx.doi.org/10.3390/toxins10090368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162461/
https://www.ncbi.nlm.nih.gov/pubmed/30208596
http://dx.doi.org/10.3390/toxins10090368

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