PDGFR and IGF-1R Inhibitors Induce a G2/M Arrest and Subsequent Cell Death in Human Glioblastoma Cell Lines

Glioblastomas are highly resistant to radiation and chemotherapy. Currently, there are no effective therapies for this type of tumor. Signaling mechanisms initiated by PDGFR and IGF-1R are important in glioblastoma, and inhibition of the signal transduction pathways initiated by these receptors coul...

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Detalles Bibliográficos
Autores principales: Carrasco-Garcia, Estefania, Martinez-Lacaci, Isabel, Mayor-López, Leticia, Tristante, Elena, Carballo-Santana, Mar, García-Morales, Pilar, Ventero Martin, Maria Paz, Fuentes-Baile, Maria, Rodriguez-Lescure, Álvaro, Saceda, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162497/
https://www.ncbi.nlm.nih.gov/pubmed/30200644
http://dx.doi.org/10.3390/cells7090131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162497/
https://www.ncbi.nlm.nih.gov/pubmed/30200644
http://dx.doi.org/10.3390/cells7090131

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