The Role of Signal Transducer and Activator of Transcription 3 (STAT3) and Its Targeted Inhibition in Hematological Malignancies

Signal transducer and activator of transcription 3 (STAT3), a member of the STAT protein family, can be phosphorylated by receptor-associated Janus kinases (JAKs) in response to stimulation by cytokines and growth factors. It forms homo- or heterodimers that can translocate to the cell nucleus where...

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Detalles Bibliográficos
Autores principales: Arora, Loukik, Kumar, Alan Prem, Arfuso, Frank, Chng, Wee Joo, Sethi, Gautam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162647/
https://www.ncbi.nlm.nih.gov/pubmed/30217007
http://dx.doi.org/10.3390/cancers10090327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162647/
https://www.ncbi.nlm.nih.gov/pubmed/30217007
http://dx.doi.org/10.3390/cancers10090327

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