Relationship between Altered miRNA Expression and DNA Methylation of the DLK1-DIO3 Region in Azacitidine-Treated Patients with Myelodysplastic Syndromes and Acute Myeloid Leukemia with Myelodysplasia-Related Changes

The DLK1–DIO3 region contains a large miRNA cluster, the overexpression of which has previously been associated with myelodysplastic syndromes (MDS). To reveal whether this overexpression is epigenetically regulated, we performed an integrative analysis of miRNA/mRNA expression and DNA methylation o...

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Detalles Bibliográficos
Autores principales: Merkerova, Michaela Dostalova, Remesova, Hana, Krejcik, Zdenek, Loudova, Nikoleta, Hrustincova, Andrea, Szikszai, Katarina, Cermak, Jaroslav, Jonasova, Anna, Belickova, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162661/
https://www.ncbi.nlm.nih.gov/pubmed/30223454
http://dx.doi.org/10.3390/cells7090138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162661/
https://www.ncbi.nlm.nih.gov/pubmed/30223454
http://dx.doi.org/10.3390/cells7090138

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