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Impacts of Indoxyl Sulfate and p-Cresol Sulfate on Chronic Kidney Disease and Mitigating Effects of AST-120

Uremic toxins, such as indoxyl sulfate (IS) and p-cresol, or p-cresyl sulfate (PCS), are markedly accumulated in the organs of chronic kidney disease (CKD) patients. These toxins can induce inflammatory reactions and enhance oxidative stress, prompting glomerular sclerosis and interstitial fibrosis,...

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Detalles Bibliográficos
Autores principales: Liu, Wen-Chih, Tomino, Yasuhiko, Lu, Kuo-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162782/
https://www.ncbi.nlm.nih.gov/pubmed/30208594
http://dx.doi.org/10.3390/toxins10090367