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Targeted Genomic Screen Reveals Focal Long Non-Coding RNA Copy Number Alterations in Cancer Cell Lines

The landscape of somatic copy-number alterations (SCNAs) affecting long non-coding RNAs (lncRNAs) in human cancers remains largely unexplored. While the majority of lncRNAs remain to be functionally characterized, several have been implicated in cancer development and metastasis. Considering the ple...

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Detalles Bibliográficos
Autores principales: Volders, Pieter-Jan, Lefever, Steve, Baute, Shalina, Nuytens, Justine, Vanderheyden, Katrien, Menten, Björn, Mestdagh, Pieter, Vandesompele, Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162788/
https://www.ncbi.nlm.nih.gov/pubmed/30217017
http://dx.doi.org/10.3390/ncrna4030021