A Critical Role for HlgA in Staphylococcus aureus Pathogenesis Revealed by A Switch in the SaeRS Two-Component Regulatory System

Cytolytic pore-forming toxins including alpha hemolysin (Hla) and bicomponent leukotoxins play an important role in the pathogenesis of Staphylococcus aureus. These toxins kill the polymorphonuclear phagocytes (PMNs), disrupt epithelial and endothelial barriers, and lyse erythrocytes to provide iron...

Descripción completa

Detalles Bibliográficos
Autores principales: Venkatasubramaniam, Arundhathi, Kanipakala, Tulasikumari, Ganjbaksh, Nader, Mehr, Rana, Mukherjee, Ipsita, Krishnan, Subramaniam, Bae, Taeok, Aman, M. Javad, Adhikari, Rajan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162840/
https://www.ncbi.nlm.nih.gov/pubmed/30231498
http://dx.doi.org/10.3390/toxins10090377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162840/
https://www.ncbi.nlm.nih.gov/pubmed/30231498
http://dx.doi.org/10.3390/toxins10090377

Ejemplares similares