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Soluble Toll-Like Receptor 4 Impairs the Interaction of Shiga Toxin 2a with Human Serum Amyloid P Component

Shiga toxin 2a (Stx2a) is the main virulence factor produced by pathogenic Escherichia coli strains (Stx-producing E. coli, STEC) responsible for hemorrhagic colitis and the life-threatening sequela hemolytic uremic syndrome in children. The toxin released in the intestine by STEC targets the globot...

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Detalles Bibliográficos
Autores principales: Brigotti, Maurizio, Arfilli, Valentina, Carnicelli, Domenica, Ricci, Francesca, Tazzari, Pier Luigi, Ardissino, Gianluigi, Scavia, Gaia, Morabito, Stefano, He, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162853/
https://www.ncbi.nlm.nih.gov/pubmed/30231570
http://dx.doi.org/10.3390/toxins10090379