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Translational Medicine in Pulmonary-Renal Crosstalk: Therapeutic Targeting of p-Cresyl Sulfate Triggered Nonspecific ROS and Chemoattractants in Dyspneic Patients with Uremic Lung Injury

Molecular mechanisms and pathological features of p-Cresyl sulfate (PCS)-induced uremic lung injury (ULI) in chronic kidney disease (CKD) remain unclear. We analyzed pleural effusions (PE) from CKD and non-CKD patients for uremic toxins, reactive oxygen species (ROS), and chemotactic cytokines. Corr...

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Detalles Bibliográficos
Autores principales: Chang, Jia-Feng, Liang, Shih-Shin, Thanasekaran, Pounraj, Chang, Hsueh-Wei, Wen, Li-Li, Chen, Chung-Hua, Liou, Jian-Chiun, Yeh, Jih-Chen, Liu, Shih-Hao, Dai, Huei-Min, Lin, Wei-Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162871/
https://www.ncbi.nlm.nih.gov/pubmed/30205620
http://dx.doi.org/10.3390/jcm7090266