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The prostaglandin D(2) receptor 2 pathway in asthma: a key player in airway inflammation

Asthma is characterised by chronic airway inflammation, airway obstruction and hyper-responsiveness. The inflammatory cascade in asthma comprises a complex interplay of genetic factors, the airway epithelium, and dysregulation of the immune response. Prostaglandin D(2) (PGD(2)) is a lipid mediator,...

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Detalles Bibliográficos
Autores principales: Domingo, Christian, Palomares, Oscar, Sandham, David A., Erpenbeck, Veit J., Altman, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162887/
https://www.ncbi.nlm.nih.gov/pubmed/30268119
http://dx.doi.org/10.1186/s12931-018-0893-x