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MicroRNA let-7c-5p Suppressed Lipopolysaccharide-Induced Dental Pulp Inflammation by Inhibiting Dentin Matrix Protein-1-Mediated Nuclear Factor kappa B (NF-κB) Pathway In Vitro and In Vivo

BACKGROUND: Let-7c-5p is down-regulated in dental pulp tissues in inflammatory disorders. The microRNA (miR) molecule shows an anti-inflammation potential due to its direct regulation of dentin matrix protein-1 (DMP1), which promotes inflammation changes in dental pulp tissues. In the present study,...

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Detalles Bibliográficos
Autores principales: Yuan, Hao, Zhang, Hong, Hong, Lihua, Zhao, Hongyan, Wang, Jiafeng, Li, He, Che, Hongze, Zhang, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162970/
https://www.ncbi.nlm.nih.gov/pubmed/30238933
http://dx.doi.org/10.12659/MSM.909093