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Alterations in the gene expression of drug and arachidonic acid-metabolizing Cyp450 in the livers of controlled and uncontrolled insulin-dependent diabetic mice

BACKGROUND: Diabetic patients have lower capacity to metabolize drugs in comparison to normal people. Therefore, the present study aimed to investigate the alterations in gene expression of drug and arachidonic acid metabolizing cytochrome p450s (cyp450s) in the livers of controlled (CDM) and uncont...

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Detalles Bibliográficos
Autores principales: Jarrar, Yazun Bashir, Al-Essa, Luay, Kilani, Abdulhasib, Hasan, Mariam, Al-Qerem, Walid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162993/
https://www.ncbi.nlm.nih.gov/pubmed/30288071
http://dx.doi.org/10.2147/DMSO.S172664