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SOX2, a stemness gene, induces progression of NSCLC A549 cells toward anchorage-independent growth and chemoresistance to vinblastine

BACKGROUND: Non-small cell lung cancer (NSCLC) is difficult to treat successfully. This intractability is mainly due to the cancer progressing through invasion, metastasis, chemotherapeutic resistance and relapse. Stemness has been linked to the various steps of cancer progression in a variety of tu...

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Detalles Bibliográficos
Autores principales: Choe, Chungyoul, Kim, Hyewon, Min, Sol, Park, Sangkyu, Seo, Jeongmin, Roh, Sangho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163012/
https://www.ncbi.nlm.nih.gov/pubmed/30288055
http://dx.doi.org/10.2147/OTT.S175810