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Targeting EGFR and uPAR on human rhabdomyosarcoma, osteosarcoma, and ovarian adenocarcinoma with a bispecific ligand-directed toxin

PURPOSE: Human sarcomas are rare and difficult to treat cancerous tumors typically arising from soft tissue or bone. Conversely, carcinomas are the most common cancer subtype in humans and the primary cause of mortality across all cancer patients. While conventional therapeutic modalities can prolon...

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Detalles Bibliográficos
Autores principales: Oh, Felix, Todhunter, Deborah, Taras, Elizabeth, Vallera, Daniel A, Borgatti, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163021/
https://www.ncbi.nlm.nih.gov/pubmed/30288129
http://dx.doi.org/10.2147/CPAA.S160262