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Prostate cancer tends to metastasize in the bone-mimicking microenvironment via activating NF-κB signaling

Prostate cancer preferentially metastasizes to the bone. However, the underlying molecular mechanisms are still unclear. To explore the effects of a bone-mimicking microenvironment on PC3 prostate cancer cell growth and metastasis, we used osteoblast differentiation medium (ODM; minimal essential me...

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Detalles Bibliográficos
Autores principales: Tong, Haibo, Zou, Chunlin, Qin, Siyuan, Meng, Jie, Keller, Evan T., Zhang, Jian, Lu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163113/
https://www.ncbi.nlm.nih.gov/pubmed/30190448
http://dx.doi.org/10.7555/JBR.32.20180035