Cargando…

Prostate cancer tends to metastasize in the bone-mimicking microenvironment via activating NF-κB signaling

Prostate cancer preferentially metastasizes to the bone. However, the underlying molecular mechanisms are still unclear. To explore the effects of a bone-mimicking microenvironment on PC3 prostate cancer cell growth and metastasis, we used osteoblast differentiation medium (ODM; minimal essential me...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tong, Haibo, Zou, Chunlin, Qin, Siyuan, Meng, Jie, Keller, Evan T., Zhang, Jian, Lu, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editorial Department of Journal of Biomedical Research 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163113/ https://www.ncbi.nlm.nih.gov/pubmed/30190448 http://dx.doi.org/10.7555/JBR.32.20180035

Ejemplares similares

Tumor microenvironment promotes prostate cancer cell dissemination via the Akt/mTOR pathway
por: Shi, Junlin, et al.
Publicado: (2018)

Intracranial Metastases Tend to Be Overt and Predict Poor Prognosis in Children With Neuroblastoma
por: Liu, Ying, et al.
Publicado: (2021)

Tpeak-Tend, Tpeak-Tend dispersion and Tpeak-Tend/QT in children and its relationship with clinical variables
por: Castro-Torres, Yaniel, et al.
Publicado: (2019)

Regulatory T cells in the bone marrow microenvironment in patients with prostate cancer
por: Zhao, Ende, et al.
Publicado: (2012)

Nanodevices Tend to Be Round
por: Pananakakis, Georges, et al.
Publicado: (2021)

Sex and race differences in J-Tend, J-Tpeak, and Tpeak-Tend intervals
por: Hnatkova, Katerina, et al.
Publicado: (2019)

Oligodendrogliomas tend to infiltrate the frontal aslant tract, whereas astrocytomas tend to displace it
por: Landers, M. J. F., et al.
Publicado: (2023)

Distinct tumor microenvironments of lytic and blastic bone metastases in prostate cancer patients
por: Ihle, Claire L., et al.
Publicado: (2019)

Tend to Compare and Tend to Be Fair: The Relationship between Social Comparison Sensitivity and Justice Sensitivity
por: Zhen, Shanshan, et al.
Publicado: (2016)

Immune mediators in the tumor microenvironment of prostate cancer
por: Dai, Jinlu, et al.
Publicado: (2017)

Cigarette smoke-associated inflammation impairs bone remodeling through NFκB activation
por: Lu, Yi, et al.
Publicado: (2021)

Engineering osteoblastic metastases to delineate the adaptive response of androgen-deprived prostate cancer in the bone metastatic microenvironment
por: Bock, Nathalie, et al.
Publicado: (2019)

Transgenerational effects and the cost of ant tending in aphids
por: Tegelaar, Karolina, et al.
Publicado: (2013)

Sacrocolpopexy tends to be superior to transvaginal mesh surgery
por: Veit‐Rubin, Nikolaus, et al.
Publicado: (2020)

Tpeak-Tend Interval during Pregnancy and Postpartum
por: Kandzia, Tomasz, et al.
Publicado: (2022)

Regulatory signaling network in the tumor microenvironment of prostate cancer bone and visceral organ metastases and the development of novel therapeutics
por: Chu, Gina Chia-Yi, et al.
Publicado: (2019)

Observations on Prostatic Cancer with Metastases in Bone
por: Charteris, Alexander A.
Publicado: (1927)

Multiple brown tumors with primary hyperparathyroidism mimicking bone metastases [1]
por: Ngo, Quy X., et al.
Publicado: (2021)

EV-Mediated Chemoresistance in the Tumor Microenvironment: Is NF-κB a Player?
por: Di Vito Nolfi, Mauro, et al.
Publicado: (2022)

NF-κB mediated regulation of tumor cell proliferation in hypoxic microenvironment
por: Rastogi, Shubham, et al.
Publicado: (2023)

Cancer Stem Cells, Bone and Tumor Microenvironment: Key Players in Bone Metastases
por: Roato, Ilaria, et al.
Publicado: (2018)

Role of the Bone Microenvironment in the Development of Painful Complications of Skeletal Metastases
por: Park, Sun H., et al.
Publicado: (2018)

miR-204-5p Represses Bone Metastasis via Inactivating NF-κB Signaling in Prostate Cancer
por: Wa, Qingde, et al.
Publicado: (2019)

Diaphragmatic peritoneal metastases mimicking liver metastases
por: Noiret, Barbara, et al.
Publicado: (2021)

Why Do Hubs Tend to Be Essential in Protein Networks?
por: He, Xionglei, et al.
Publicado: (2006)

Stars rich in heavy metals tend to harbor planets
Publicado: (2003)

Tending Adam's garden: evolving the cognitive immune self
por: Cohen, Irun R
Publicado: (2004)

Tending Wounded Belligerents under the Protection of the Convention of Geneva
Publicado: (1912)

Some Social Factors That Tend to the Degeneration of the Race and Alcoholism
por: Kime, R. R.
Publicado: (1903)

Languages with more speakers tend to be harder to (machine-)learn
por: Koplenig, Alexander, et al.
Publicado: (2023)

Prostate Cancer and Bone Metastases: The Underlying Mechanisms
por: Wong, Sok Kuan, et al.
Publicado: (2019)

The relationship between length of stay in intensive care unit and Tpeak‐Tend and Tpeak‐Tend/QTc ratio in COVID 19 patients with acute coronary syndrome
por: Altuntas, Emine, et al.
Publicado: (2022)

Breast cancer bone metastases are attenuated in a Tgif1-deficient bone microenvironment
por: Haider, Marie-Therese, et al.
Publicado: (2020)

Advancing Treatment of Bone Metastases through Novel Translational Approaches Targeting the Bone Microenvironment
por: Sethakorn, Nan, et al.
Publicado: (2022)

Bone Microenvironment‐Suppressed T Cells Increase Osteoclast Formation and Osteolytic Bone Metastases in Mice
por: Arellano, Danna L., et al.
Publicado: (2022)

Multifocal musculoskeletal tuberculosis mimicking multiple bone metastases: a case report
por: Ye, Meiping, et al.
Publicado: (2016)

Prostate carcinoma presenting with diffuse osteolytic metastases and supraclavicular lymphadenopathy mimicking multiple myeloma
por: Idowu, Bukunmi Michael
Publicado: (2017)

Gene expression profile analysis of the bone microenvironment in patients with spinal metastases
por: Liu, Wangmi, et al.
Publicado: (2018)

Housekeeping genes tend to show reduced upstream sequence conservation
por: Farré, Domènec, et al.
Publicado: (2007)

Remarks Tending to Elucidate the History of Erysipelas, and Especially of Phlegmonous Erysipelas
por: Corbin,
Publicado: (1831)

Cannot write session to /tmp/vufind_sessions/sess_v1antg7273usotuhupefakt22i