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Pretreatment with simvastatin upregulates expression of BK-2R and CD11b in the ischemic penumbra of rats
Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductases, collectively known as statins, have been shown to minimize cerebral ischemic events in patients. We assessed the mechanisms of simvastatin pretreatment in preventing cerebral ischemia/reperfusion injury in rats using a model of middle c...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Editorial Department of Journal of Biomedical Research
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163114/ https://www.ncbi.nlm.nih.gov/pubmed/29784898 http://dx.doi.org/10.7555/JBR.32.20160152 |