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Pretreatment with simvastatin upregulates expression of BK-2R and CD11b in the ischemic penumbra of rats

Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductases, collectively known as statins, have been shown to minimize cerebral ischemic events in patients. We assessed the mechanisms of simvastatin pretreatment in preventing cerebral ischemia/reperfusion injury in rats using a model of middle c...

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Detalles Bibliográficos
Autores principales: Zhang, Jianying, Bai, Qingke, Zhang, Yingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163114/
https://www.ncbi.nlm.nih.gov/pubmed/29784898
http://dx.doi.org/10.7555/JBR.32.20160152

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