Induction of p53 Phosphorylation at Serine 20 by Resveratrol Is Required to Activate p53 Target Genes, Restoring Apoptosis in MCF-7 Cells Resistant to Cisplatin

Resistance to cisplatin (CDDP) is a major cause of cancer treatment failure, including human breast cancer. The tumor suppressor protein p53 is a key factor in the induction of cell cycle arrest, DNA repair, and apoptosis in response to cellular stimuli. This protein is phosphorylated in serine 15 a...

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Detalles Bibliográficos
Autores principales: Hernandez-Valencia, Jorge, Garcia-Villa, Enrique, Arenas-Hernandez, Aquetzalli, Garcia-Mena, Jaime, Diaz-Chavez, Jose, Gariglio, Patricio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163170/
https://www.ncbi.nlm.nih.gov/pubmed/30142917
http://dx.doi.org/10.3390/nu10091148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163170/
https://www.ncbi.nlm.nih.gov/pubmed/30142917
http://dx.doi.org/10.3390/nu10091148

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