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Heterogeneity of γH2AX Foci Increases in Ex Vivo Biopsies Relative to In Vivo Tumors

The biomarker for DNA double stand breaks, gammaH2AX (γH2AX), holds a high potential as an intrinsic radiosensitivity predictor of tumors in clinical practice. Here, two published γH2AX foci datasets from in and ex vivo exposed human head and neck squamous cell carcinoma (hHNSCC) xenografts were sta...

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Detalles Bibliográficos
Autores principales: Rassamegevanon, Treewut, Löck, Steffen, Baumann, Michael, Krause, Mechthild, von Neubeck, Cläre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163410/
https://www.ncbi.nlm.nih.gov/pubmed/30181446
http://dx.doi.org/10.3390/ijms19092616