Cargando…

Specific Antibody Fragment Ligand Traps Blocking FGF1 Activity

Fibroblast growth factor 1 (FGF1) and its receptors (FGFRs) regulate crucial biological processes such as cell proliferation and differentiation. Aberrant activation of FGFRs by their ligands can promote tumor growth and angiogenesis in many tumor types, including lung or breast cancer. The developm...

Descripción completa

Detalles Bibliográficos
Autores principales: Chudzian, Julia, Szlachcic, Anna, Zakrzewska, Malgorzata, Czub, Miroslawa, Pustula, Marcin, Holak, Tad A., Otlewski, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163658/
https://www.ncbi.nlm.nih.gov/pubmed/30134556
http://dx.doi.org/10.3390/ijms19092470