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Calcium Chloride Modified Alginate Microparticles Formulated by the Spray Drying Process: A Strategy to Prolong the Release of Freely Soluble Drugs
Alginate (ALG) cross-linking by CaCl(2) is a promising strategy to obtain modified-release drug delivery systems with mucoadhesive properties. However, current technologies to produce CaCl(2) cross-linked alginate microparticles possess major disadvantages, such as a poor encapsulation efficiency of...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163791/ https://www.ncbi.nlm.nih.gov/pubmed/30149531 http://dx.doi.org/10.3390/ma11091522 |