Telocinobufagin and Marinobufagin Produce Different Effects in LLC-PK1 Cells: A Case of Functional Selectivity of Bufadienolides

Bufadienolides are cardiotonic steroids (CTS) identified in mammals. Besides Na(+)/K(+)-ATPase inhibition, they activate signal transduction via protein–protein interactions. Diversity of endogenous bufadienolides and mechanisms of action may indicate the presence of functional selectivity and uniqu...

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Detalles Bibliográficos
Autores principales: Amaral, Luciana S., Martins Ferreira, Jainne, Predes, Danilo, Abreu, José Garcia, Noël, François, Quintas, Luis Eduardo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163863/
https://www.ncbi.nlm.nih.gov/pubmed/30223494
http://dx.doi.org/10.3390/ijms19092769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163863/
https://www.ncbi.nlm.nih.gov/pubmed/30223494
http://dx.doi.org/10.3390/ijms19092769

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