Bombyx mori Dihydroorotate Dehydrogenase: Knockdown Inhibits Cell Growth and Proliferation via Inducing Cell Cycle Arrest

Dihydroorotate dehydrogenase (DHODH), in the de novo pyrimidine biosynthetic pathway, is the fourth enzyme of pyrimidine synthesis and is used to oxidize dihydroorotate and hence to orotat. We cloned and characterized here the dhod of silkworms, Bombyx mori. The full-length cDNA sequence of dhod is...

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Detalles Bibliográficos
Autores principales: Zhao, Erhu, Jiang, Xiaolan, Cui, Hongjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163951/
https://www.ncbi.nlm.nih.gov/pubmed/30200251
http://dx.doi.org/10.3390/ijms19092581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163951/
https://www.ncbi.nlm.nih.gov/pubmed/30200251
http://dx.doi.org/10.3390/ijms19092581

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